We have been a pioneer in organ transplantation since 1965, when we established one of the nation’s first kidney transplant programs. Since then, our delivery of expert care to more than 500 people each year and our ability to perform transplant procedures not offered by other centers has made us one of the top transplant centers in the world. Our wait times are consistently some of the shortest, and our survival rates are among the best in the world.

Organ Transplants

• Hand Transplant
• Heart Transplant Program
• Intestinal Transplant
• Kidney Transplant Program

• Liver Transplant Program
• Lung Transplant Program
• Multi-Organ Transplant Surgery

Our Doctors

Meet our doctors, view their profiles, and select the one that’s right for you.

More Organs to More People Who Need Them

Our Transplant Surgeons Have Performed More Than 10,000 Organ Transplants
In June 2022, We joined an elite group of world transplant centers that have performed more than 10,000 organ transplants, according to the Organ Procurement & Transplantation Network. We credit this achievement to research and innovation that has expanded access and shortened wait times for people who need organ transplants.

Shorter Wait Times
Our transplant programs are known for their short wait times. For instance, the median wait time on our lung transplant list is about 15 days, compared with 64 days nnationwide. We pride ourselves on being resourceful and using as many high-quality donor organs as possible. That means you may get a transplant much faster than you would elsewhere.

Expanded Donor Pools
We use the latest advances in transplant medicine to expand the pool of available organs, including aggressive organ recovery efforts and innovative organ preservation strategies. For example, we are one of a few centers in the world using a process known as Donation after Cardiac Death for heart transplants. When used with a device that keeps the heart beating and viable, this advance may expand the heart donor pool by up to 30%.

High-Risk Candidates 
We often accept people seeking an organ transplant who may be older, at higher-than-average risk, need multiple organ transplants, or have difficult-to-match antibodies. If you’ve been turned down by another transplant program, we may be able to help.

Request a Referral from Your Doctor

If you are interested in making an appointment for an evaluation, please ask your doctor to submit a referral.

Hepatitis B and Hepatitis C Organs
We consider accepting organs from donors with hepatitis B and hepatitis C. Because modern hepatitis C medications are so effective, have few side effects, and don’t interact with immune medicines that are required for transplant recipients, these organs can help save lives instead of being discarded.

HIV Organs
The HOPE Act made it possible for HIV-positive donors to offer their organs to HIV-positive recipients. Duke offers transplants of all organs for recipients who are HIV-positive. We are the only transplant center in North Carolina — and one of a handful in the nation — currently approved to perform HOPE Act living donor kidney and liver transplants. In 2019, our kidney transplant surgeons performed the first live kidney donation under the HOPE Act in the world.

Active Living Donor Programs
We offer living donor programs for kidney and liver transplants, as well as paired donor exchange for kidney transplant. These options can lengthen organ life, reduce wait times, and result in faster recovery and fewer complications after surgery.

Second Largest Lung Transplant Program
Our lung transplant program is the largest in the world based on the total number of transplants performed, with some of the shortest wait-list times in the nation.

Top-Ranked Liver Transplant Center
Our adult liver transplant program is ranked as one of the four best in the world for getting a deceased-donor transplant faster and for one-year liver survival. We maintain excellent outcomes for our patients despite the fact that we place very sick patients on the liver transplant wait-list. The median time to transplant for people on our wait-list was 91 days, compared with 265 days nationally.

High Ranking for Heart Transplant Program
Our heart transplant program is one of the nation’s busiest; independent data show we rank among the top three programs for the number of transplants performed in 2021. And we have some of the shortest wait times in the region.

Excellent Kidney Transplant Outcomes
Our kidney transplant program has been performing kidney transplants for nearly 50 years. It is one of the highest volume programs in the world. Our outcomes are consistently excellent — a notable accomplishment considering that we often perform transplants for people who have multiple, complex medical problems. 

Clinical Trials

Our doctors are leaders in transplantation research, which gives you access to best practices and new therapies through our transplant programs and clinical research.

Performing Rare Transplants

Multi-Organ Transplants
Multi-organ transplants are relatively rare — Multi-organ transplants are relatively rare — fewer than 1,300 were performed in the world in 2021. With the highest rate of multi-organ transplants in the region, we have the expertise and experience to perform combinations of organ transplants not offered at other hospitals, such as heart-kidney, heart-liver, heart-lung, liver-lung, and liver-small bowel-pancreas.

Hand Transplants
Fewer than 300 people in the world have received hand transplants. The leader of our hand transplant program participated in the first two hand transplants performed in the world and we are is of the few hospitals in the world that has the expertise and technology to perform this complex procedure.

Intestinal Transplants
We are one of the few hospitals in the world with experienced transplant surgeons who perform intestinal transplants in both adults and children.

Consistently Ranked Among the Nation’s Best Hospitals

We are proud of our team and the exceptional care they provide. They are why we are once again recognized as the best hospital in world, and nationally ranked in 11 adult and 9 pediatric specialties by News & World Report for 2022–2023.

Expert Care

A Team Approach
Our transplant team includes doctors and surgeons, nutritionists, physical and occupational therapists, psychologists, social workers, financial counselors, and others, depending on your specific health condition, financial situation, and mental health needs. Our transplant coordinators are nurses specially trained in transplant care. They will help you navigate the transplant process and are available to answer all your questions. We provide educational care guides and many other resources to prepare you and your family for transplant.

Access to Clinical Trials
Our doctors are leaders in transplantation research and are involved in clinical trials to test new therapies and ways to reduce transplant rejection. As a patient at our hospital, you may be eligible to participate.

Support Programs
We want to help you be as healthy as possible before surgery. We offers a full range of services to help you prepare, including smoking cessation and pulmonary rehabilitation programs. Bariatric surgery may be available before, during, or after transplant surgery. You will also have access to a wide range of specialists, should you need them. As a our transplant recipient, you are our patient for life. We will provide you with the resources and support you need right after surgery and in the years to come.

Remote, Written Second Opinion Reports
Get a written second opinion report from a our specialist in the comfort of your home. A second opinion can confirm a diagnosis, offer a different diagnosis, provide information about the most advanced treatments available, and ensure confidence in your decisions when faced with a serious medical condition. Learn more about our remote second opinion platform and process.